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Symptom Checker » Itchy macular rash » Metabolic disorder

Itchy macular rash and Metabolic disorder
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Results: Causes of Itchy macular rash AND Metabolic disorder

    1. Alkaptonuria
     A rare disorder where the abnormal accumulation of a particular acid (homogentisic acid) in the body causes connective tissue and bone damage. This damage gives tissues a dark or bluish more »

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Results: Causes of Itchy macular rash OR Metabolic disorder

    1. 3?-hydroxysteroid dehydrogenase deficiency
     A ver rare form of congenital adrenal hyperplasia involving a deficiency of 3?-hydroxysteroid dehydrogenase which results in reduced production of adrenal steroids (mineralocorticoids, sex steroids and glucocorticoids). The disorder can occur in classical...more »
    2. Acid phosphatase deficiency
     A group of inherited metabolic bone disorders varying in degree of severity and characterized a deficiency of alkaline phosphate which affects bone mineralization....more »
    3. Alkaptonuria
     A rare disorder where the abnormal accumulation of a particular acid (homogentisic acid) in the body causes connective tissue and bone damage. This damage gives tissues a dark or bluish discoloration....more »
    4. Barth Syndrome
     A rare genetic disorder where the body's cells are unable to make sufficient energy resulting in an accumulation in the body of 3-methylglutaconic acid. Type 2 is characterized by its affects on the heart....more »
    5. Becker's nevus
     A rare skin disorder where an irregular pigmented patch on the skin slowly grows and becomes thick and hairy....more »
    6. Biotinidase deficiency
     A metabolic disorder where the body lacks the enzyme biotinidase needed to process the vitamin called biotin (vitamin H) into carboxylase enzymes....more »
    7. Erythrasma
     A condition where there is a bacterial skin infection that is located in the armpits or the groin...more »
    8. Farber's disease
     A rare inherited biochemical disorder involving the deficiency of an enzyme called ceramidase resulting in the harmful accumulation of certain chemicals in the body which causes damage and inflammation....more »
    9. Galactosemia I
     A rare inherited disorder where deficiency of a particular enzyme (galactose-1-phosphate uridyl transferase) prevents the metabolism of galactose which is a sugar component of milk. Ranges from milk intolerance in mild cases to death in severe untreated c...more »
    10. Gaucher Disease
     A rare inherited biochemical disorder characterized by the deficiency of the enzyme called glucocerebrosidase and accumulation of glycosylceramide (glucocerebroside). There are three forms of this disease: type 1, 2 and 3....more »
    11. Glucose-6-Phosphate Dehydrogenase Deficiency
     A rare enzyme abnormality involving a deficiency of the glucose-6-phosphate dehydrogenase which causes premature destruction of red blood cells. The excessive destruction of red blood cells can be triggered by certain infections or drugs or by eating fava...more »
    12. Glutathione Synthetase Deficiency
     An inborn error of metabolism where insufficient glutathione is produced. Glutathione is an antioxidant which helps destroy unstable molecules that can cause damage to cells and helps develop certain cell components. The condition is due to insufficient g...more »
    13. Glycogen storage disease type 2
     A rare inherited biochemical disorder involving the harmful accumulation of certain chemicals (glycogen) in body tissues due to the deficiency of an enzyme (?-glucosidase or acid maltase) needed to break it down....more »
    14. Glycogen storage diseases
     A condition which is characterized by a defect in the ability of the body to store glycogen...more »
    15. Hereditary amyloidosis
     An inherited form of amyloidosis which is characterized by a build up of the protein amyloid in tissues and organs. This form of amyloidosis tends to affect mainly the nervous system and gastrointestinal tract. Symptoms are determined by the size and loca...more »
    16. High Cholesterol
     High levels of blood cholesterol, triglycerides, or other lipids....more »
    17. Homocystinuria
     A rare inherited metabolic disorder involving the amino acid methionine and resulting in a harmful accumulation of homocysteine in the body....more »
    18. Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome
     A very rare inherited metabolic disorder where ammonia builds up in the body due to a defect in the transport of ornithine which prevents ammonia being converted to urea and being excreted through the urine. The severity of the condition is variable....more »
    19. Lentigo maligna
     Lentigo maligna is a melanoma in situ that consists of malignant cells but does not show invasive growth.....more »
    20. Leprosy
     A chronic, progressive infectious disease caused by Mycobacterium leprae which causes skin sores and also affects the eyes, mucous membranes and peripheral nerves....more »
    21. Maple syrup urine disease
     A very rare inherited metabolic disorder involving abnormal metabolism of branched chain amino acids (leucine, isoleucine and valine) and resulting in severe illness which generally leads to death if not treated. Other milder variants of the disease do ex...more »
    22. Measles
     Once common viral infection now rare due to vaccination....more »
    23. Mitochondrial myopathy -- lactic acidosis
     A very rare syndrome characterized mainly by muscle disease and a metabolic disorder. The severity and progression of the disease is variable with some dying early in their second decade and others living longer....more »
    24. Mucopolysaccharidoses
     A lysosomal storage disorder that is caused by a deficiency of the ability to metabolise glycosaminoglycans...more »
    25. Non-ketotic hyperglycinemia
     A rare disorder of amino acid metabolism where glycine and proline are unable to be metabolized properly due to defects in the glycine cleavage system....more »
    26. Oxalosis
     A rare inherited metabolic disorder where excess oxalic acid forms crystals which make up urinary stones. In type I primary hyperoxaluria there is a deficiency of peroxisomal alanine-glyoxalate aminotransferase and type II involves a deficiency of the enz...more »
    27. Phenylketonuria -- Teratogenic Agent
     There is strong evidence to indicate that the development of Phenylketonuria during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by th...more »
    28. Piebaldism
     A rare genetic condition characterized by patches of lack of pigmentation that involves the skin and the hair....more »
    29. Porphyria
     A group of disorders characterized by excess production of porphyrin or its precursors which affects the skin and/or nervous system....more »
    30. Pyruvate carboxylase deficiency
    31. Rheumatic fever
     An inflammatory disorder that can occur as a complication of untreated streptococcal bacterial infection such as strep throat or scarlet fever. The condition may affect the brain, skin, heart and joints....more »
    32. Roseola infantum
     Contagious infant conditions...more »
    33. Rubella
     A contagious viral infection caused by the Rubella virus which produces a rash and lymph node swelling. It can have serious implication in pregnant women as the virus can be transmitted through the placenta and cause serious fetal defects or even fetal de...more »
    34. Syphilis -- Teratogenic Agent
     There is strong evidence to indicate that the development of Syphilis during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the stage...more »
    35. Systemic Juvenile Rheumatoid Arthritis
     Onset of JRA with fevers and systemic symptoms...more »
    36. Tinea versicolor
     A condition which is characterized by a chronic noninflammatory multiple macular patches...more »
    37. Tuberous sclerosis
     A rare genetic disorder characterized by harmartomatous skin nodules, seizures, phakomata and bone lesions....more »
    38. Tyrosinemia
     A rare genetic metabolic disorder characterized by a deficiency of particular enzymes which prevents the breakdown of tyrosine which then builds up in the liver....more »
    39. Urea Cycle Disorders
     Any disorder that affects the urea cycle....more »
    40. Viral exanthema
     Viral exanthema is a widespread skin rash triggered by a viral infection. These rashes are more common in children than adults. The rashes are usually not itchy....more »
    41. Vitiligo in infants
     Condition where areas of de-pigmented (whitened) skin develops; occurs in people of all races and skin colours but more noticeable on darker skinned individuals...more »
    42. Wolman disease
     A rare inherited lipid storage disease. The condition usually results in death early in life....more »
    43. Zellweger Syndrome
     Zellweger spectrum disorders are a group of rare, genetic, multisystem disorders that were once thought to be separate entities. These disorders are now classified as different expressions (variants) of one disease process. Collectively, they form a spect...more »

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